Study Finds CBD has Beneficial Effects in Patients with Schizophrenia

Cannabidiol (CBD) has beneficial effects in patients with schizophrenia, according to a new study published by the American Journal of Psychiatry

“Research in both animals and humans indicates that cannabidiol (CBD) has antipsychotic properties”, begins the study’s abstract. “The authors assessed the safety and effectiveness of CBD in patients with schizophrenia.”

In an exploratory double-blind parallel-group trial, patients with schizophrenia were “randomized in a 1:1 ratio to receive CBD (1000 mg/day; N=43) or placebo (N=45) alongside their existing antipsychotic medication.” Participants were “assessed before and after treatment using the Positive and Negative Syndrome Scale (PANSS), the Brief Assessment of Cognition in Schizophrenia (BACS), the Global Assessment of Functioning scale (GAF), and the improvement and severity scales of the Clinical Global Impressions Scale (CGI-I and CGI-S).”

After 6 weeks of treatment, compared with the placebo group, “the CBD group had lower levels of positive psychotic symptoms (PANSS: treatment difference=-1.4, 95% CI=-2.5, -0.2) and were more likely to have been rated as improved (CGI-I: treatment difference=-0.5, 95% CI=-0.8, -0.1) and as not severely unwell (CGI-S: treatment difference=-0.3, 95% CI=-0.5, 0.0) by the treating clinician.” Patients who received CBD “also showed greater improvements that fell short of statistical significance in cognitive performance (BACS: treatment difference=1.31, 95% CI=-0.10, 2.72) and in overall functioning (GAF: treatment difference=3.0, 95% CI=-0.4, 6.4). CBD was well tolerated, and rates of adverse events were similar between the CBD and placebo groups.”

The study concludes by stating that; “These findings suggest that CBD has beneficial effects in patients with schizophrenia. As CBD’s effects do not appear to depend on dopamine receptor antagonism, this agent may represent a new class of treatment for the disorder.”

The full study, published online by the U.S. National Institute of Health, can be found by clicking here.

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from https://thejointblog.com/study-finds-cbd-beneficial-effects-patients-schizophrenia/…

12 Stoner Songs for the High Holidaze

For cannabis enthusiasts—especially in California, where 2018 will mark the legalization of “adult use” sales—who really want to celebrate the holiday season, “yule” get higher than a partridge in a pear tree listening to the following dozen seasonal tokin’ tunes.

1. DENT MAY: “I’LL BE STONED FOR CHRISTMAS” 

L.A.-by-way-of Mississippi ukulele auteur Dent May evokes Phil Spector’s Wall of Sound with this poppy piano-driven ode to being home for the holidays. “So I’m trying to get lifted with you now/We broke into my cousin’s stash/We’re having a blast,” he sings “Got an angel on my treetop/And a devil on my mind/Have a smoke and pour a big shot/’Tis the season to be high.” Being the nice young man he is, Dent then apologizes to his mother.

2. ADAM SANDLER: “THE CHANUKAH SONG”

Originally written for Saturday Night Live in 1994, this has become Jewish stoners’ favorite holiday number (to go along with the “Dreidel” song). “So drink your gin and tonic-ah,” Sandler jokes. “And smoke your marijuana-kah.” His riotous roll call of famous members of the tribe includes “All three Stooges!” 

3. WILLIE

North Dakota Initiative to Legalize Marijuana Approved by Secretary of State

North Dakota Secretary of State Al Jaeger on Friday approved for circulation an initiative to legalize marijuana for everyone 21 and older.

Proponents of the initiative must now collect around 13,500 signatures from registered North Dakota voters in order to put it to a vote of the people during the November, 2018 general election. The proposal would legalize the possession, personal cultivation and licensed distribution of recreational marijuana for everyone who is at least 21 years old.

The measure would also seal the records of anyone who’s been convicted of a marijuana-related crime that would be made legal under the initiative.

If advocates of the measure are successful in placing it on the ballot, and voters approve it, North Dakota would become the ninth state to legalize cannabis.

The post North Dakota Initiative to Legalize Marijuana Approved by Secretary of State appeared first on TheJointBlog.

from https://thejointblog.com/north-dakota-initiative-legalize-marijuana-approved-secretary-state/…

Bermuda Senate Approves Legislation to Decriminalize Cannabis, Sending it to Governor

Just days after the Bermuda House of Assembly overwhelmingly approved legislation to decriminalize small amounts of cannabis, the Senate has done the same.

The legislation, titled the Misuse of Drugs (Decriminalization of Cannabis) Amendment Act and tabled by Minister of Social Development and Sport Zane DeSilva, will decriminalize the possession of up to seven grams of cannabis for personal use. Given the measure has been approved by Bermuda’s full Congress, it now goes to Governor John Rankin for consideration. Rankin is expected to sign the measure into law.

Under the proposed law cannabis possession up to seven grams would no longer be a criminal offense, though police would still have the authority to seize any cannabis found on a person. Charges could also still be applied if it’s determined that the cannabis was intended to be distributed, rather than consumed for personal use. The minister will also be tasked with determining regulations for substance abuse education or treatment for those caught possessing cannabis.

According to a Profiles of Bermuda poll released in 2015, 79% of voters in Bermuda support either decriminalizing or legalizing cannabis.

The post Bermuda Senate Approves Legislation to Decriminalize Cannabis, Sending it to Governor appeared first on TheJointBlog.

from https://thejointblog.com/bermuda-senate-approves-legislation-decriminalize-cannabis-sending-governor/…

First Recreational Marijuana Business Licenses Issued in California

Yesterday California’s Bureau of Cannabis Control issued the first licenses for recreational marijuana businesses, paving the way for legal marijuana sales to begin the beginning of next year.

“This is a great Christmas present,” said California NORML director Dale Gieringer. “Licensing is an inevitable necessity of the modern bureaucratic state. I’m just happy to see the stores open and people be able to walk into a store — any adult including tourists and guests in California — and get cannabis just like they can get alcohol, cigarettes or all sorts of wonderful things in California.”

Altogether 20 licenses were issued to cannabis businesses located throughout the state, including multiple located in San Diego, Lynwood and San Jose. The most – seven in total – are located in Santa Cruz.

Below is a list of the 20 licenses issued yesterday (list provided by GreenState.com):

 

Legal Business Name Record Type Status
Pure CA, LLC Adult-Use – Distributor Temporary License Active LYNWOOD CA 90262
Pure CA, LLC Medicinal – Distributor Temporary License Active LYNWOOD CA 90262
Buddy’s Cannabis Medicinal – Microbusiness Temporary License Active 1075 10TH ST N, BLDG, SAN JOSE CA 95112
HERBL Distribution Solutions Medicinal – Distributor Temporary License Active SANTA ROSA CA 95403
Buddy’s Cannabis Adult-Use – Microbusiness Temporary License Active 1075 10TH ST N, BLDG, SAN JOSE CA 95112
Golden State Sciences Medicinal – Distributor Temporary License Active  KING CITY CA 93930
Yes Cannabis – Laboratory Testing Temporary License Active 181 HUNTINGTON DR W, SUITE 106, MONROVIA CA 91016
Torrey Holistics Medicinal – Retailer Temporary License Active 10671 ROSELLE ST, SUITE 100, SAN DIEGO CA 92121
KindPeoples (formerly KindPeoples Collective) Medicinal – Distributor Temporary License Active SANTA CRUZ CA 95060
KindPeoples (formerly KindPeoples Collective) Adult-Use – Distributor Temporary License Active SANTA CRUZ CA 95060
Torrey Holistics Adult-Use – Retailer Temporary License Active 10671 ROSELLE ST, SUITE 100, SAN DIEGO CA 92121
KindPeoples Medicinal – Retailer Temporary License

Build Your Custom Dab Tool Kit During TAG’s Holiday Sale

If you’re a dabber looking for the best dab tools or cheapest dab rigs then coming to Thick Ass Glass’ holiday sale is going to be your best choice of the year. As an experienced dabber, you know that the right tools can make or break a good dabbing session, and that quality tools make for a better dab.

So when you’re looking at 30% off the entire store at TAG, with everything from dab rigs to ceramic nails and quartz bangers to dabbers on sale, you’re going to come out a winner. Here are just a few highlights for folks who love the dabbing scene:

Quartz Bangers

TAG big quartz bangerOne of the beautiful things about TAG is that we don’t just stock “the same old” when it comes to smoking and dabbing accessories. A prime example we should talk about here is probably the TAG 30x2mm Quartz Banger. Now, it’s important to note that this is a freakin’ big banger.

If you’re new to the dabbing game, we probably would recommend AGAINST such a huge banger, but seasoned pros asked for this particular bucket, and TAG provided. Not only is this thick, high quality quartz… it’s also laser engraved with the TAG logo. And hey, who can doubt the words of TAG customer Felixe B., who notes, “It’s lit”.

Yes Felixe. It is.

Quartz bangers aren’t always the same old at TAG, as we noted. A good example might be the TAG Quartz Trough High Flow Banger, a super thick, completely fantastic “trough shaped” banger that is simply going to change your dabbing style forever. This is FDA Grade Quartz crystal at its best, or as customer John S. puts it, “Way better than any of the headshop quartz I’ve had and for a lot less money.”

We like your attitude, John.

Dabbers

Let’s face it… A dabbing enthusiast without a decent dabber/carb cap combo is like a knight …

Massachusetts Cannabis Control Commission Begins Public Discussion of Marijuana Regulations

The Massachusetts Cannabis Control Commission has begun its public policy discussion for the retail marijuana regulations to implement Question 4. While we will address a few items during the upcoming public hearings, the first few days have generally shown encouraging results! The commission has looked at a variety of issues around marijuana business licensing and has made a few key determinations already:

  • Businesses that derive more than 50% of revenue from marijuana may apply for a social consumption license, which would allow on-site consumption of marijuana. Other businesses that derive less than 50% of their revenue from cannabis sales may apply for a mixed-use license and may only sell marijuana in conjunction with another service, such as a restaurant, spa, movie theater, or yoga studio.

 

  • The regulations will give priority review to business license applicants who have lived in areas disproportionately impacted by marijuana prohibition and who hire employees that live in areas of disproportionate impact. This change will help the communities that have been most affected by the racial disparity in enforcement of marijuana prohibition.

 

  • Applicants will receive priority for hiring people with prior drug convictions.

 

These decisions show the Cannabis Control Commission’s willingness to address the problems created by marijuana prohibition and the racial disparity in its enforcement, and we applaud their willingness to craft a fair and effective regulatory scheme. The commission will continue looking at draft regulations through next week, at which point the rules will be open for public comment. The final regulations are slated for March of next year.

The post Massachusetts Cannabis Control Commission Begins Public Discussion of Marijuana Regulations appeared first on MPP Blog.

from https://blog.mpp.org/tax-and-regulate/massachusetts-cannabis-control-commission-begins-public-discussion-marijuana-regulations/…

World Health Organization Says CBD Shouldn’t be a Controlled Substance

The United Nations’ World Health Organization (WHO) says that current information doesn’t justify cannabidiol (CBD), a compound found in cannabis, being a controlled substance.

“There is increased interest from Member States in the use of cannabis for medical indications including for palliative care”, states the WHO report released yesterday. “Responding to that interest and increase in use, WHO has in recent years gathered more robust scientific evidence on therapeutic use and side effects of cannabis and cannabis components. To that end, the ECDD [Expert Committee on Drug Dependence] did an initial review of a cannabis compound called cannabidiol (CBD).”

The report claims that “Recent evidence from animal and human studies shows that its use could have some therapeutic value for seizures due to epilepsy and related conditions. The ECDD therefore “concluded that current information does not justify scheduling of cannabidiol”.

The committee “postponed a fuller review of cannabidiol preparations to May 2018, when the committee will undertake a comprehensive review of cannabis and cannabis related substances.”

The post World Health Organization Says CBD Shouldn’t be a Controlled Substance appeared first on TheJointBlog.

from https://thejointblog.com/world-health-organization-says-cbd-shouldnt-controlled-substance/…

Bermuda House Passes Bill to Decriminalize Cannabis Possession

Bermuda’s House of Assembly has overwhelmingly approved legislation to decriminalize small amounts of cannabis.

The Misuse of Drugs (Decriminalization of Cannabis) Amendment Act, tabled by Minister of Social Development and Sport Zane DeSilva, would decriminalize the possession of up to seven grams of cannabis for personal use. The measure now goes to the Senate for consideration. Passage in the Senate would send it to Governor John Rankin who could sign it into law, allow it to become law without his signature, or veto it.

Although police would no longer be able to arrest individuals with up to seven grams of cannabis under the proposed law, they could still seize it. The minister would also be tasked with drawing up regulations for substance abuse education or treatment for those caught possessing cannabis.

According to a Profiles of Bermuda poll released in 2015, 79% of voters in Bermuda support either decriminalizing or legalizing cannabis.

The post Bermuda House Passes Bill to Decriminalize Cannabis Possession appeared first on TheJointBlog.

from https://thejointblog.com/bermuda-house-passes-bill-decriminalize-cannabis-possession/…

Study: Cannabis May Help HIV Patients Keep Mental Stamina Longer

A new study published in the journal AIDS has found that THC can potentially slow the process in which mental decline can occur in up to 50% of HIV patients.

“It’s believed that cognitive function decreases in many of those with HIV partly due to chronic inflammation that occurs in the brain,” says Norbert Kaminski, lead author of the study which was conducted at Michigan State University. “This happens because the immune system is constantly being stimulated to fight off disease.”

According to Science Daily, Kaminski and his co-author, Mike Rizzo, a graduate student in toxicology, discovered that the compounds in marijuana were able to act as anti-inflammatory agents, reducing the number of inflammatory white blood cells, called monocytes, and decreasing the proteins they release in the body.

“This decrease of cells could slow down, or maybe even stop, the inflammatory process, potentially helping patients maintain their cognitive function longer,” Rizzo said.

The two researchers took blood samples from 40 HIV patients who reported whether or not they used marijuana. Then, they isolated the white blood cells from each donor and studied inflammatory cell levels and the effect marijuana had on the cells.

“The patients who didn’t smoke marijuana had a very high level of inflammatory cells compared to those who did use,” Kaminski said. “In fact, those who used marijuana had levels pretty close to a healthy person not infected with HIV.”

Kaminski, director of MSU’s Institute for Integrative Toxicology, has studied the effects of marijuana on the immune system since 1990. His lab was the first to identify the proteins that can bind marijuana compounds on the surface of immune cells. Up until then, it was unclear how these compounds, also known as cannabinoids, affected the immune system.

HIV, which stands for human immunodeficiency virus, infects and can destroy or change the functions of immune cells that defend the body. With antiretroviral therapy — a standard …