CBD May Help Treat Methamphetamine Dependency, States New Study

Cannabidiol (CBD) can “reduce the motivation to seek and consume methamphetamine”, suggesting it may be effective as a treatment for those addicted to the drug, finds a new study published by the Journal of Psychopharmacology.

“Methamphetamine is an addictive stimulant that can cause many adverse physical, psychological and psychosocial effects”, begins the study’s abstract. “Preliminary evidence shows cannabidiol, a non-intoxicating constituent of the cannabis plant, may have efficacy in treating opioid and nicotine dependence. However, no study has yet examined whether cannabidiol treatment might impact on methamphetamine addiction.”

The current study “investigated whether cannabidiol administration reduces the motivation to self-administer methamphetamine and relapse to methamphetamine-seeking behavior following abstinence.”

Thirty-two male Sprague Dawley rats with implanted jugular vein catheters were initially trained to self-administer methamphetamine via lever press during two-hour sessions on a fixed ratio 1 schedule of reinforcement. Rats in experiment 1 ( n=16) then advanced to a progressive ratio reinforcement schedule to examine the effects of cannabidiol (0, 20, 40, and 80 mg/kg intraperitoneal) on motivation to self-administer methamphetamine. Rats in experiment 2 ( n=16) were tested for cannabidiol effects on methamphetamine-primed reinstatement following extinction.

“Cannabidiol (80 mg/kg, but not 40 mg/kg, or 20 mg/kg) reduced the motivation to self-administer methamphetamine and attenuated methamphetamine-primed relapse to methamphetamine-seeking behavior after extinction”, states the study.

According to researchers,. this is the first demonstration “that cannabidiol can reduce the motivation to seek and consume methamphetamine, and suggests that cannabidiol might be worth trialing as a novel pharmacotherapy for methamphetamine dependence.”

The full study, conducted by researchers at Macquarie University and the University of Syndey, can be found by clicking here.

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Here is the Most Expensive Bong in the World

The most expensive bong in the world (pictured below) is available now for just $1 million!

The website selling The Throne states that it’s considered to be “one of the most iconic and legendary functional glass pieces in the industry”. Standing nearly two feet tall, the piece was constructed in 2010. The skulls were made by Scott Deppe, and remove from the top to reveal the mouthpiece. The structure was assembled by Darby Holm using the Deppe’s Darkness color.” Banjo, the third collaborator, “constructed the one foot tall goddess that sits upon Darby’s lattice of bones.”

The airflow of this piece “begins at the push bowl, where it travels down into a large natural percolator and then on up the skeletal backbone to the mouthpiece.” Since this piece was first exhibited, “there have been several similar pieces created, but this one will always be considered the true original.”

The Throne can be viewed at Illuzion Glass Galleries in Denver, Colorado, and can be purchased online by clicking here.

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Study: Cannabis Oil Reduces Seizures, Improves Quality of Life, in Those with Dravet Syndrome

According to a new study, cannabis oil (containing both CBD and THC) is effective in reducing seizure counts and improving quality of life measures in those with Dravet Syndrome.

An epilepsy word cloud.

The study, titled A prospective open-label trial of a CBD/THC cannabis oil in dravet syndrome, was published by the journal Annals of Clinical and Translational Neurology.  According to the Dravet Foundation, dravet syndrome, also known as Severe Myoclonic Epilepsy of Infancy (SMEI), “is a rare and catastrophic form of intractable epilepsy that begins in infancy”, with “an estimated incidence rate of 1:16,000 to 1:21,000”.

The study’s abstract starts by stating that “Both Δ9 Tetrahydrocannabidiol (THC) and cannabidiol (CBD) components of cannabis, have been shown to have anticonvulsant effects. Cannabis oils are used to treat seizures in drug-resistant epilepsy (DRE).” It then goes on to note that “Recent trials provide data on dosing, side effects, and efficacy of CBD, yet there is a paucity of information on THC in epilepsy.”

The primary objective of the study “was to establish dosing and tolerability of TIL-TC150 – a cannabis plant extract produced by Tilray®, containing 100 mg/mL CBD and 2 mg/mL THC- in children with Dravet syndrome. Secondary objectives were to assess impact of therapy on seizures, electroencephalogram (EEG) and quality of life.”

For the study, twenty children “received add-on therapy with TIL-TC150. The dose ranged from 2 to 16 mg/kg/day of CBD and 0.04 to 0.32 mg/kg/day of THC. Patients were monitored for tolerability and adverse events, and secondary objectives.”

Nineteen participants completed the 20-week intervention. Mean dose achieved was 13.3 mg/kg/day of CBD (range 7-16 mg/kg/day) and 0.27 mg/kg/day of THC (range 0.14-0.32 mg/kg/day).

“There was a statistically significant improvement in quality of life, reduction in EEG spike activity, and median motor seizure reduction of 70.6%, with 50% responder rate of 63%”, states the study.

Researchers  conclude; “TIL-TC150 was safe and …

Medical Cannabis for Pets Bill Signed Into Law by California Governor

California Governor Jerry Brown has signed into law legislation that explicitly allows and regulates the medical use of cannabis for pets.

Assembly Bill 2215 was given approval by the full Senate in August by a vote of 37 to 1 vote, roughly three months after the Assembly passed it 60 to 10.  Governor Brown signed the measure into law yesterday.

Assembly Bill 2215 would expand “the intent of the Medicinal and Adult-Use Cannabis Regulation and Safety Act (MAUCRSA) to control and regulate cannabis and cannabis products for medicinal use on pets.” It would define “cannabis products” to include products intended for medicinal use on a pet, and although it wouldn’t allow a veterinarian to administer medical cannabis, it  would “allow a veterinarian to discuss the use of cannabis on an animal for medicinal purposes without being disciplined or denied, revoked or suspended by the Veterinary Medical Board (VMB).”

The measure states that the VMB “would have until July 1, 2019 to promulgate guidelines for veterinarians to follow when discussing the use of cannabis”, and it “Provides that a cannabis product for use on a pet may only be sold to an adult 21 years or age or over by a licensee who has been issued a retailer license, as specified.”

The full text of Assembly Bill 2215 can be found by clicking here.

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The Top 15 Fun Things To Do While High | HonestMarijuana

Woman smoking weed & thinking about things to do while high

Being high is pretty damn great all by itself. But sometimes just sitting there stewing in your own psychedelic juices isn’t enough. You need something more. That’s when you start looking for fun things to do while high.

And while recreating the stunts from Jackass, making a backyard wrestling video, or taunting a badger is never a good idea, there are plenty of less dangerous activities that make being high even better than it already is.

Top 15 Fun Things To Do While High

1) Dance

Yes, gravity (and couch lock) can be rough, but you’ll enjoy your high more if you get up and move once in a while. Pick a type of music that gets your foot tapping, crank up the volume, and let your body move to the beat.

2) Tai Chi

Capitalize on your heightened awareness by learning and performing some Tai Chi. You’ll be more aware of your breathing, your heartbeat, and the flow of energy from head to toe and back again. That’ll make Tai Chi, and being high, more stimulating.

3) Hula Hoop

Hula-hooping as one of the things to do while high

We never could hula hoop sober. But after a few tokes on an Honest Blunt, we could damn near turn pro (if that were a thing…which it should be). There’s something extremely satisfying about finding the rhythm in your hips that keeps that hoop spinning.

Add in a bit of your favorite music, and the experience will be transcendent.

4) Go To The Circus

Sure, you probably got your fill of the circus when you were a kid, and now it’s nothing special. But the circus can be seriously mind-blowing again if you hit your bong first.

Don’t have a circus near you? Really, anything with a lot of movement and flashy colors will work (e.g., Cirque du Soleil, Stomp). And if you really have no other options, stick in The Greatest Showman and get your fix that way.…

Chart: The History of U.S. State Marijuana Ballot Initiatives


On the 2018 Ballot

Mormons Oppose Marijuana Initiative in Utah Despite History of Cannabis Use

Michigan Is Poised to Become the 10th State to Legalize It

Dueling Initiatives in Missouri Likely to Confuse Voters

Recreational Legalization on the North Dakota Ballot

If you enjoyed this Freedom Leaf article, subscribe to the magazine today!

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Ask candidates for the Maryland Legislature to commit to supporting marijuana policy reform

The latest Goucher poll shows that 62% of Marylanders “support the legalization of marijuana for recreational use.” Unfortunately, Maryland’s lawmakers have lagged behind the public on this issue — but this could change in November’s election. If you are a Maryland voter,  please let the candidates in your district know that this issue is important to you. (And don’t forget to check out the Maryland Cannabis Policy Coalition’s Voter Guide here.)

If you are interested in hearing more about MPP’s work — and meeting our new executive director, Steven Hawkins — please consider attending the Spark! Maryland networking event on October 4 at 6:30 p.m. at The Reserve at Two Rivers, 4105 Mountain Road, Pasadena, MD 21122. You can purchase tickets here.

Marylanders are ready to join the eight other states that have legalized and regulated marijuana for adults 21 and older. Click here to ask the people who want to represent you in the General Assembly if they’re ready too.

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Rick Steves to tour Michigan in support of legalization ballot measure

Next week, legendary travel host Rick Steves will be visiting Michigan to give talks in support of Prop 1, the ballot initiative to legalize and regulate marijuana. Known for his hit PBS series “Rick Steves’ Europe,” Rick’s engaging personality and first-hand experience seeing the benefits of legalization in his home state of Washington make this an event you don’t want to miss.

You can catch him in two locations, Grand Rapids and Ann Arbor. Both speaking events are free and open to the public. The tour schedule is listed below.

TUESDAY, OCTOBER 2
It’s Time for a New Approach: Rick Steves on why legalization is a better solution
Time: 7:30 p.m., doors at 7:00 p.m.
Location: Peter Martin Wege Theatre, 341 Ellsworth Ave. SW, Grand Rapids
Cost: FREE
Register here

WEDNESDAY, OCTOBER 3
It’s Time for a New Approach: Rick Steves on why legalization is a better solution
Time: 8:30 p.m., doors at 8:00 p.m.
Location: Rackham Amphitheatre, 915 E Washington St., Ann Arbor
Cost: FREE
Register here

As a board member of NORML, Rick Steves has been a long-time advocate for sensible marijuana policies. Audiences around the country have heard his informative and entertaining talks on marijuana legalization, and now you have a chance to see him, too. Register for one of the events above and share the word by inviting friends and family.

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How Long Does Weed High Last: The Definitive Answer

Clocks telling how long does weed high last

If there’s one question that everyone seems to wonder about — but no one knows the answer to — it’s, “How long does weed high last?” If you’re new to the world of marijuana, don’t feel bad asking this question. Even many long-time cannaseurs have a hard time giving a conclusive answer.

But not us! We know what you want to hear. So in this article, the cannabis experts at Honest Marijuana give you the definitive answer to the question how long does weed high last.

How Long Does Weed High Last?

The best way to answer that question is by saying, “It depends…” We know that’s not very definitive, but let us finish. Before you get angry and storm off, the duration of your weed high really does depend on the way you consume your THC.

What that means is that you can tailor your experience by choosing from among the many different methods of getting THC into our body. Once you decide that, we can give you a much more definitive answer to your question.

Here’s how the durations break down based on method of consumption.

Smoking

Smoking is one of the most common ways to get your ganja on. The tools used for smoking are literally legion and include:

Basically, any time you inhale the smoke or vapor from a marijuana product, you’re smoking.

How long does a smoking weed high last? 1-3 hours

Edibles

Woman who's high on weed

There are so many ways to make your marijuana into edibles that you’re really only limited by your creativity. Our favorite edibles include:

Yes, that’s right. Milk, tea, and pills are included on this list. Basically, anything that you put in your mouth and swallow can be considered an edible.

How long does an edibles weed high last? 4-6 …

NY: Medical marijuana program adds acute pain management as qualifying condition

On Monday, September 24, Gov. Andrew Cuomo signed a bill that adds acute pain management to the list of approved conditions eligible for treatment with medical marijuana as an alternative to opioid use. This new law formalizes regulations the New York State Department of Health issued in July, which added opioid replacement and opioid use disorder to the list.

This is great news for patients! Access to medical marijuana is no longer limited to those suffering from chronic pain. This bill and regulations allow more patients who could benefit from medical marijuana a safe and effective alternative to highly addictive opioids.

Find more information on New York’s medical marijuana program, including the list of qualifying conditions and how to register, here.

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Study: Cannabinoids May Inhibit Tumor Growth in Triple Negative Breast Cancer

According to a new study published by the journal Photodiagnosis and Photodynamic Therapy, cannabinoids may inhibit tumor growth in triple negative breast cancer.

The study states that “Triple negative breast cancer (TNBC) is the deadliest form of breast cancer because compared with other types of breast cancer, it is more aggressive, diagnosed at later stage and more likely to develop recurrence”. Many patients “do not experience adequate tumor control after current clinical treatments involving surgical removal, chemotherapy and/or radiotherapy, leading to disease progression and significantly decreased quality of life.”

Here researchers “report a new combinatory therapy strategy involving cannabinoid-based medicine and photodynamic therapy (PDT) for the treatment of TNBC.” They found that “the combined CB2R agonist and TSPO-PDT treatment resulted in synergistic inhibition in TNBC cell and tumor growth.”

The study concludes; “This combinatory therapy approach provides new opportunities to treat TNBC with high efficacy. In addition, this study provides new evidence on the therapeutic potential of CB2R agonists for cancer.”

For the full study, click here.

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New York Governor Signs Bill Adding Pain Management to List of Medical Cannabis Conditions

Governor Andrew Cuomo yesterday signed legislation (S8987A/A 11011-B) that adds acute pain management to the list of conditions for which medical marijuana can be recommended as an alternative to opioid use.

The bill will also allow for substance use disorder treatment providers to recommend medical marijuana to help patients manage underlying pain that contributes to the abuse of substances such as opioids.

“In this battle against the opioid epidemic, it is critical that we use every means at our disposal to prevent the unnecessary prescription of these dangerous and addictive painkillers,” Governor Cuomo said. “Adding these conditions to the list of those approved for management with medical marijuana will help reduce the risk of addiction and provide suffering New Yorkers the relief they need.”

“We know that medical marijuana can be a helpful alternative for a wide range of illnesses and conditions,” said Lieutenant Governor Kathy Hochul. “By expanding the approved list, we are providing New Yorkers with new options, and preventing the danger that comes from opioid addiction.”

The bill will formalize into law the regulatory change that was implemented by the Department of Health earlier this year that added opioid replacement and opioid use disorder to the existing list of conditions for which a patient can qualify for medical marijuana. In order to recommend medical marijuana for pain management, a registered practitioner must determine that the patient’s pain degrades health and functional capability, along with certain other requirements.

Senator George Amedore, Chairman of the Senate Standing Committee on Alcoholism and Substance Abuse said, “As the Senate Task Force on Heroin and Opioid Addiction travelled the state, this was a big gap that we heard about over and over. When we look at solutions to help us combat the heroin and opioid epidemic, we must ensure prescribers and patients have every resource and option at their disposal. I’m glad the Governor has signed this legislation that will help patients …

Mormons Oppose Marijuana Initiative in Utah Despite History of Cannabis Use

Mormons with Mexicans in Northern Mexico, 1908

In 1885, the prophet and president of the Mormon Church, John Taylor, purchased about 100,000 acres of land in Mexico—in Chihuahua and Sonora, to be exact, some 200 miles south of the US border. More than 300 polygamous Mormon families from Utah migrated south to settle the land and to proselytize (even today you see the traveling twosomes of fresh-faced young men in their white shirts, ties and black name tags) and, many theorize, to preserve the practice of polygamy.

At the time, Mormon polygamists were being jailed and having their property seized. Utah itself was denied statehood by the federal government to halt the practice. Former presidential candidate Mitt Romney is descended from the Mexican settlements; his father, George, and grandfather, Marion, were born in Colonia Dublán, Mexico, in 1907.

But in 1910, many who had settled in northern Mexico began an exodus back to Utah due to anti-American sentiment fueled by the Mexican Revolution. Some say they returned with a local plant introduced by the natives: cannabis.

The Mormon Church, formally known as the Church of Jesus Christ of Latter-Day Saints (LDS), were and still are infamous for their teetotaler ways and as abstainers of vices of all kinds; hence, they didn’t look kindly on the brethren partaking of the plant, viewing it as a violation of Mormon scripture from the “Doctrine and Covenants,” section 89 (D&C 89), commonly referred to as the “Word of Wisdom.”

Michigan legalization campaign wins a big endorsement

Great news! The Detroit Free Press, one of Michigan’s largest media outlets, has endorsed the Yes on 1 legalization campaign!

The paper’s supportive editorial echoed many of the Yes on 1 campaign’s core messages: marijuana prohibition wastes law enforcement resources, unfairly harms communities of color, and prevents the state from collecting millions in tax revenue that could fund critical social programs. This is a huge boost for Prop 1, but we have to make sure the momentum is carried forward into November.

You can help the Yes on 1 team by making a donation here. Supporters can also promote the effort by picking up Yes on 1 gear from the new campaign store. There, you’ll find some great items, including t-shirts, hoodies, and yard signs, with the official Yes on 1 logo.

We’re just a few weeks away from Election Day (November 6). Michigan residents should visit the Secretary of State’s voter page to get information about polling locations, absentee voting, and more. The deadline to register to vote is October 9. If you’re not already registered, click here for the registration form. Be sure to fill it out and deliver it to your city or town clerk’s office by October 9.

If you have friends or family in Michigan, please forward this email to them and ask them to vote “Yes” on Prop 1. I’m confident that if enough people pitch in, we’ll be celebrating another major victory on November 6.

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Study: CBD Could Prevent Haloperidol-Induced Orofacial Dyskinesia

Cannabidiol (CBD) may prevent haloperidol-induced orofacial dyskinesia, according  to new research being published by the journal Brain, Behavior, and Immunity; the research was epublished by the National Institute of Health.

“The chronic use of drugs that reduce the dopaminergic neurotransmission can cause a hyperkinetic movement disorder called tardive dyskinesia (TD)”, states the study’s abstract. “The pathophysiology of this disorder is not entirely understood but could involve oxidative and neuroinflammatory mechanisms. Cannabidiol (CBD), the major non-psychotomimetic compound present in Cannabis sativa plant, could be a possible therapeutic alternative for TD.”

The study states that “This phytocannabinoid shows antioxidant, anti-inflammatory and antipsychotic properties and decreases the acute motor effects of classical antipsychotics. The present study investigated if CBD would attenuate orofacial dyskinesia, oxidative stress and inflammatory changes induced by chronic administration of haloperidol in mice.”

Furthermore, researchers “verified in vivo and in vitro (in primary microglial culture) whether these effects would be mediated by PPARγ receptors. The results showed that the male Swiss mice treated daily for 21 days with haloperidol develop orofacial dyskinesia. Daily CBD administration before each haloperidol injection prevented this effect.”

Mice treated with haloperidol “showed an increase in microglial activation and inflammatory mediators in the striatum. These changes were also reduced by CBD. ”

The study concludes by stating that; “In conclusion, our results suggest that CBD could prevent haloperidol-induced orofacial dyskinesia by activating PPARγ receptors and attenuating neuroinflammatory changes in the striatum.”

For the full study, click here.

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Seattle Court Agrees to Expunge Past Marijuana Convictions

Judges in Seattle have agreed to clear past misdemeanor convictions for marijuana possession that were prosecuted before marijuana was legalized in Washington, reports the Seattle Times.

All seven judges of the Seattle Municipal Court have signed an order setting out a process for vacating the cases. The ruling follows City Attorney Pete Holmes’ filing of a motion in April asking the court to vacate the convictions.

In his motion, Holmes argued that possessing small amounts of marijuana is no longer illegal and clearing past convictions would right the injustices of a drug war that targeted people of color.

About 542 people could be affected. The ruling covers from about 1996 – when municipal courts, rather than county district courts, began handling those misdemeanors – to 2010 when Holmes became city attorney and stopped prosecuting low-level, non-violent marijuana cases.

“Insomuch as the conduct for which the defendant was convicted is no longer criminal, setting aside the conviction and dismissing the case serves the interests of justice,” wrote the judges in their ruling.

“For too many who call Seattle home, a misdemeanor marijuana conviction or charge has created barriers to opportunity — good jobs, housing, loans and education,” said Mayor Jenny Durkan in a public statement.  “While we cannot reverse the harm that was done, we will continue to give Seattle residents a clean slate.”

The post Seattle Court Agrees to Expunge Past Marijuana Convictions appeared first on TheJointBlog.

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New Study Provides Evidence Supporting the Use of Cannabinoids to Treat Prostate Cancer

Cannabinoids may provide a potential treatment option for prostate cancer, according to a new study published by the journal The Prostate.

“Cannabinoids have demonstrated anticarcinogenic properties in a variety of malignancies, including in prostate cancer”, states researchers. In the present study, they “explored the anti-cancer effects of the synthetic cannabinoid WIN 55,212-2 (WIN) in prostate cancer.”

For the study, “Established prostate cancer cells (PC3, DU145, LNCaP) were treated with varying concentrations of WIN”, and “Cell proliferation was determined by the MTS assay.” The anti-migration and anti-invasive potential of WIN “was examined by the wound healing assay and the matrigel invasion assay.” Cell cycle analysis was performed by flow cytometry, and mechanistic studies were performed by Western blot.

Animals were randomized into two groups: saline control and WIN (5 mg/kg), delivered by intraperitoneal injection three times per week for 3 weeks.

“WIN significantly reduced prostate cancer cell proliferation, migration, invasion, induced apoptosis, and arrested cells in Go/G1 phase in a dose-dependent manner”, claim researchers.

They conclude; “The following study provides evidence supporting the use of WIN as a novel therapeutic for prostate cancer.”

For more info on this study, click here.

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What Is THC? And Why Is It So Good?

Tetrahydrocannabinol structural formula

There’s no getting high off the good ole green without THC, but what is THC and how does it work?

Most smokers have heard this buzzword before, but not many know its chemical composition or the science behind how THC affects that brain and body. Every cerebral buzz you feel from smoking a well-packed bowl or leisurely spliff is directly proportional to the cannabis plant’s THC concentration. But why is that?

In this article, the experts at Honest Marijuana tell you all the dirty details you’ll need to know to become an authority on all things THC (at least in your own head). Along the way, we’ll discuss such essential topics as:

  • What is THC?
  • How was THC discovered?
  • How does THC affect your brain?
  • How does THC affect your body?
  • How does potency affect the experience?
  • What are some common ways to consume THC?
  • How is THC medicinal?

That’s a lot to cover! So light up a toke and get ready to tuck in as we unearth the secrets of one of nature’s best beauties.

What Is THC?

Delta-9-tetrahydrocannabinol (THC) is a chemical secreted by the glands of the marijuana plant. It is found in high doses around the reproductive organs, as well as in the resin glands of the bud or flower of the female pot plant.

Although THC is only one of 85 plus chemical compounds known as cannabinoids found in the cannabis plant, THC is the primary psychoactive ingredient. It takes almost all the credit for creating your cerebral high.

Delta-9-tetrahydrocannabinolSource: Leafscience.com

Whereas humans use THC to get high, marijuana plants use THC to fend off natural predators like parasites, bacteria, and viruses. THC doesn’t produce antibacterial properties in people but, CBG (cannabigerol) a non-psychoactive compound also found in cannabis, does. Dr. Mary Jane always makes sure we get exactly what we need from our weed.

Study: Daily Marijuana Use Associated With Increased Treatment Retention Rates for Those Addicted to Opioids

Daily cannabis use is associated with greater odds of retention in treatment among those addicted to opioids, according to a new study published in the journal Addiction, and epublished online by the National Institute of Health.

cannabis “Cannabis use is common among people on opioid agonist treatment (OAT), causing concern for some care providers”, states the study. “However, there is limited and conflicting evidence on the impact of cannabis use on OAT outcomes. Given the “critical role of retention in OAT in reducing opioid-related morbidity and mortality”, researchers “aimed to estimate the association of at least daily cannabis use on the likelihood of retention in treatment among people initiating OAT.” As a secondary aim researchers “tested the impacts of less frequent cannabis use.”

The study comprised a total of 820 people who use illicit drugs (PWUD), who initiated OAT between December 1996 and May 2016. . Participants were followed for a median of 81 month.

The primary outcome was retention in OAT, defined as remaining in OAT (methadone or buprenorphine/naloxone-based) for two consecutive 6-month follow-up periods, and the primary explanatory variable was cannabis use (at least daily versus less than daily) during the same 6-month period. “Confounders assessed included: socio-demographic characteristics, substance use patterns and social-structural exposures.”

In adjusted analysis, “at least daily cannabis use was positively associated with retention in OAT [adjusted odds ratio (aOR) = 1.21, 95% confidence interval (CI) = 1.04-1.41]. Our secondary analysis showed that compared with non-cannabis users, at least daily users had increased odds of retention in OAT (aOR = 1.20, 95% CI = 1.02-1.43), but not less than daily users (aOR = 1.00, 95% CI = 0.87-1.14).”

Researchers conclude from this that “Among people who use illicit drugs initiating opioid agonist treatment in Vancouver, at least daily cannabis use was associated with approximately 21% greater odds of retention in treatment compared with less than daily consumption.”

More information on this study, …

Study: THC/CBD Effective in Treating Pain From Failed Back Surgery Syndrome

According to a new study published by the Journal of Pain Research, THC/CBD can have “remarkable analgesic capabilities” in the treatment of chronic refractory pain caused by failed back surgery syndrome.

“This study aimed to evaluate pain and its symptoms in patients with failed back surgery syndrome (FBSS) refractory to other therapies, treated with a combination of delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD), in association with spinal cord stimulation (SCS)”, states the study’s abstract. “Outpatients referred at Pain Unit of San Vincenzo Hospital in Taormina (Italy), between September 2014 and January 2016”, were evaluated.

For the study, eleven FBSS patients diagnosed with neuropathic pain, and suffering from moderate to severe chronic refractory pain and undergoing treatment with SCS and a combination of THC/CBD for 12 consecutive months, completed the Douleur Neuropathique 4 questionnaire.

“All the included patients discontinued previous unsuccessful therapy at least 2 months before the beginning of the cannabinoid therapy, with the exception of the SCS that was continued. Patients received a fixed dosage of cannabinoid agonists (THC/CBD) that could be increased subjective to pain control response.” A Brief Pain Inventory questionnaire “was administered to measure pain and its interference with characteristic dimensions of feelings and functions”, and the “duration of treatment with SCS and THC/CBD combination was 12 months.”

Researchers found that “Effective pain management as compared to baseline result was achieved in all the cases studied. The positive effect of cannabinoid agonists on refractory pain was maintained during the entire duration of treatment with minimal dosage titration. Pain perception, evaluated through numeric rating scale, decreased from a baseline mean value of 8.18±1.07-4.72±0.9 by the end of the study duration (12 months) (P<0.001).”

The study concludes by stating that “The results indicate that cannabinoid agonists (THC/CBD) can have remarkable analgesic capabilities, as adjuvant of SCS, for the treatment of chronic refractory pain of FBSS patients.”

For the full study, click here.

Gauging the Cannabis Industry at Green Market Summit

From left: Vivien Azer, Debra Borchardt, Emily Paxhia, Jessica Billingsly, Jeannette Ward Horton, Cynthia Salarizadeh and Tahira Rehmatullah

“This is the most interesting investment concept today,” TV personality Jim Cramer said about the high-flying cannabis industry as he kicked off the Green Market Summit at New York’s World Trade Center on Sept. 14.

Industry experts shared a vision of legal cannabis as a trillion dollar-plus disruptor of the pharmaceutical, food and beverage industries as more Fortune 500 companies take aim at the sector. Panel topics focused on the economics of cannabis, reaching out to consumers and the potential for marijuana to become more mainstream.

One major theme of the one-day conference that drew about 200 people centered around the growing role of Fortune 500 companies in the space, such as Constellation Brands and Molson Coors.

“Rob Sands is a very smart guy,” Cramer said about Constellation’s CEO, who inked a $4 billion deal with Canopy Growth over the summer to produce non-alcoholic cannabis beverages in Canada. It’s the largest investment yet by any major company in cannabis, but more are expected. Constellation owns Corona, Mondavi and many other alcohol brands.

Northern Mariana Islands Governor Signs Marijuana Legalization Bill Into Law

Northern Mariana Islands Governor Ralph DLG. Torres has signed HB 20-178, the Taulamwaar Sensible CNMI Cannabis Act of 2018, into law.

“Today, our people made history”, said Governor Torres is a public statement. “We took a stand to legalize marijuana in the CNMI for recreational, medical, and commercial use”.

Torres’ signature on the measure comes shortly after it passed the Senate 6-0-2; it passed the House in August 108-1-1.

The new law allows those 21 and older to possess up to an ounce of marijuana, while also possessing up to 16 ounces of marijuana infused food products and 72 ounces of marijuana infused liquids. Licensed cannabis retail outlets are authorized to distribute the plant.

Under the new law there must be a Cannabis Commission appointed within 30 days. Once formed, the commission will have 180 days to create and adopt rules for the program.

Gover Torres’ signature of HB 20-178 makes the Northern Mariana Islands  the first US territory to legalize cannabis.

The post Northern Mariana Islands Governor Signs Marijuana Legalization Bill Into Law appeared first on TheJointBlog.

from https://thejointblog.com/northern-mariana-islands-governor-signs-marijuana-legalization-bill-into-law/…

U.S. territory to legalize, regulate marijuana!

The remote U.S. territory of the Northern Mariana Islands is so far ahead of the mainland U.S., it’s already late evening there. And the Northern Mariana Islands are also far ahead of the mainland U.S. when it comes to reforming marijuana laws.

The Northern Marianas just made history when it became the first jurisdiction in the U.S. where a governing body enacted legislation to both end marijuana prohibition and establish a system of regulation to replace it! Earlier today, Gov. DLG Torres signed the Taulamwaar Sensible CNMI Cannabis Act of 2018, after it was approved overwhelmingly by the commonwealth’s House and Senate.

All eight state laws that legalized, taxed, and regulated marijuana passed by voter initiative. And earlier this year, the Vermont Legislature enacted a bill that legalized adult-use possession and cultivation of marijuana. However, unlike the Northern Marianas’, Vermont’s law doesn’t include sales. (MPP spearheaded six of those nine campaigns.)

We’re proud of our allies at Sensible CNMI and lawmakers in the Northern Marianas for crafting a comprehensive, thoughtful bill that includes home cultivation, micro-producers, and on-site consumption. And we were honored to play a supporting role.

Check out our summary of the bill here.

Meanwhile, the New Jersey Legislature could enact a law to legalize and regulate marijuana soon. Please consider making a generous donation to MPP so we can convince lawmakers in other states and territories to follow the Northern Marianas’ lead!

The post U.S. territory to legalize, regulate marijuana! appeared first on MPP Blog.

from https://blog.mpp.org/tax-and-regulate/u-s-territory-to-legalize-regulate-marijuana/…

Floyd Prozanski Wants to Divert Oregon’s Primo Weed to Other Legal States

State Senator Floyd Prozanski is one of the Oregon’s legislative leaders and chair of the State Senate’s judiciary committee. He’s been heavily involved in crafting the state’s social-use legislation as well as its retail medical-marijuana program. He’ll be appearing at the International Cannabis Business Conference (ICBC) in Portland on Sept. 28. We conducted this interview with on Sept. 14.

How is Oregon dealing with its reported marijuana surpluses and what some describe as excessive cultivation licensing?

In 2017, my Senate Bill 1042, which passed out of the Senate Judiciary Committee that I chair, was going to give the governor what I call a tool in her toolbox to be able to enter into compacts with adjacent, adjoining states that had marijuana programs, either or both medical and recreational, and allow for the flow of cannabis products across state lines. I believe Oregon that the quality and the strains we produce in the medical arena would be in high demand for patients and individuals in the adjacent states. Unfortunately, the Senate leadership moved it to another committee for more consideration and it was not able to get out of that committee.

You’re talking about making Oregon-grown cannabis available in adjoining legal states like California and Washington?

Yes. Clearly, what we’d be doing at that point would be establishing a method to allow for these transfers to occur that would not be in violation of interstate commerce. To do that, we would to move the product from the Oregon into one of the three adjacent states that do have marijuana programs: California, Nevada and Washington. It would have to be through ground transportation only, because the federal government regulates air travel and marine travel.

“Allow cannabis to be available throughout the country. That would take away all of the diversion issues.”

This would allow us to address a lot of the concerns the Feds have regarding illegal diversion, because we would …